Objective-To evaluate changes over time in owner-perceived, weighted quality-of-life assessments in dogs with spinal cord injuries and determine whether scores were associated with underlying etiology or with veterinarian-assigned scores for severity of neurologic dysfunction. Design-Cohort study. Animals-100 dogs with spinal cord injury. Procedures-Duration of dysfunction, modified Frankel neurologic injury score, and etiology were recorded.
Evaluation of a questionnaire for obtaining owner-perceived, weighted quality-of-life assessments for dogs with spinal cord injuries.
Objective-To evaluate a questionnaire for obtaining owner-perceived, weighted quality-oflife assessments for dogs with spinal cord injuries. Design-Evaluation study. Animals-100 dogs with spinal cord injuries and 48 healthy control dogs. Procedures-The questionnaire was adapted from a questionnaire (the schedule for the evaluation of individual quality of life-direct weighting) used for human patients.
CASE DESCRIPTION: A 5-year-old neutered male English Bulldog was evaluated for intermittent closed-mouth jaw locking of approximately 1 week's duration. CLINICAL FINDINGS: Initial physical examination revealed a nonpainful inability to open the jaw with and without manual assistance; however, manipulation of the jaw after the dog was sedated for diagnostic imaging restored jaw function. Anesthesia was subsequently induced, and computed tomography was performed with the jaw open and closed; contrast agent-enhanced images of the closed jaw were also obtained.
Journal: Vet Radiol Ultrasound
The aim of this study was to describe the normal ultrasonographic appearance of the iliopsoas muscle and related landmarks. Hind limbs of five dog cadavers with no history of lameness were evaluated. The origin and mid-body of the psoas major and the common insertion of the iliacus and psoas major on the lesser trochanter of the femur were identified and evaluated. New methylene blue was injected under ultrasonographic guidance at the three sites. Dissection was performed to confirm placement of the dye.
Effects of firocoxib, meloxicam, and tepoxalin on prostanoid and leukotriene production by duodenal mucosa and other tissues of osteoarthritic dogs.
OBJECTIVE: To evaluate the in vivo effects of firocoxib, meloxicam, and tepoxalin on prostaglandin (PG) and leukotriene production in duodenal mucosa and other target tissues in dogs with chronic osteoarthritis (OA). ANIMALS: 8 dogs with chronic, unilateral OA of the stifle joint. PROCEDURES: In a crossover design, each dog received placebo (no treatment), firocoxib, meloxicam, or tepoxalin for 7 days, followed by a 21-day washout period.
Noninvasive determination of body segment parameters of the hind limb in Labrador Retrievers with and without cranial cruciate ligament disease.
OBJECTIVE: To determine mass, center of mass (COM), and moment of inertia (ie, body segment parameters [BSPs]) of hind limb segments by use of a noninvasive method based on computerized tomography (CT) in Labrador Retrievers with and without cranial cruciate ligament (CCL) disease and to provide regression equations to estimate BSPs of normal, CCL-deficient, and contralateral hind limbs. ANIMALS: 14 clinically normal and 10 CCL-deficient Labrador Retrievers. PROCEDURES: Bone, muscle, and fat areas were identified via CT.
Effects of clinically relevant concentrations of glucosamine on equine chondrocytes and synoviocytes in vitro.
OBJECTIVE: To evaluate the effects of glucosamine on equine articular chondrocytes and synoviocytes at concentrations clinically relevant to serum and synovial fluid concentrations. SAMPLE POPULATION: Articular cartilage and synovium with normal gross appearance from metacarpophalangeal and metatarsophalangeal joints of 8 horses (1 to 10 years of age). PROCEDURES: In vitro chondrocyte and synoviocyte cell cultures from 8 horses were treated with glucosamine (0.1 to 20 microg/mL) with or without interleukin-1 (IL-1; 10 ng/mL) for 48 hours.
Comparison of two-dimensional and three-dimensional systems for kinematic analysis of the sagittal motion of canine hind limbs during walking.
OBJECTIVE: To test the hypotheses that kinematic data of the sagittal motion of canine hind limbs during walking obtained with a 2-dimensional (2-D) system correlate well with those obtained with a 3-dimensional (3-D) system and that the data obtained with the 2-D system are repeatable. ANIMALS: 6 adult dogs with no evidence of lameness. PROCEDURES: Hind limb motions of 6 walking dogs were recorded via 2-D video and 3-D optoelectric systems simultaneously.
Objectives: To evaluate the diagnostic merits of scintigraphy in dogs with clinically obscure lameness origin. Methods: In 43 dogs, the scintigraphic findings were compared with the results of subsequent radiological, computed tomography and/or arthroscopic findings and/or additional neurological examination. Results: In all dogs, focal increased uptake was found in one or more joints or bones. The presence of associated pathology was confirmed by radiography, computed tomography and/or arthroscopy of the limb region of interest.