A standard of therapy for osteosarcoma includes amputation with or without adjuvant chemotherapy. There is a subset of dogs with osteosarcoma that are unsuitable for amputation. We evaluated kinetic variables in dogs with appendicular osteosarcoma treated with a single 8 Gy dose of radiation. Eighteen pet dogs with appendicular osteosarcoma received one 8 Gy fraction of palliative radiation on day 0. Force plate measurements and clinical assessments were made on days 0, 7, 14, and 21. Peak vertical forces (Fz) were recorded for each limb and a symmetric index (SI) was calculated.
Oncology
Journal: Vet Surg
OBJECTIVE: To characterize biologic behavior, clinical outcome, and effect of histologic grade on prognosis for dogs with appendicular chondrosarcoma treated by amputation alone. STUDY DESIGN: Case series. ANIMALS: Dogs (n=25) with appendicular chondrosarcoma. METHODS: Medical records were searched to identify dogs with appendicular chondrosarcoma treated by limb amputation alone. Information recorded included signalment, anatomic location, radiographic appearance, and development of metastasis. Histopathologic diagnosis was confirmed and graded (1, 2, or 3).
Category: Oncology
Journal: Vet Surg
OBJECTIVE: To (1) evaluate the analgesic effect of percutaneous cementoplasty (PC) in dogs with primary bone tumor (PBT) of the distal aspect of the radius and (2) evaluate the impact on the course of disease by adding PC to a palliative, multimodal treatment protocol in these dogs. STUDY DESIGN: Prospective pilot study. ANIMALS: Dogs (n=4) with PBT of the distal aspect of the radius. METHODS: Tumor lesions were filled percutaneously with polymethylmethacrylate under fluoroscopic guidance. Pamidronate was administered once in a week before PC.
Category: Distal Extremities - Fracture Fixation and Implants - Oncology
Journal: VCOT
Rim resection of mandibular tumours and a simplified technique using a biradial osteotomy blade for maxillary tumours in dogs has not previously been described. The medical records and radiographs of dogs with mandibular (n = 3) or maxillary (n = 1) tumours resected using crescentic osteotomies were reviewed. The owners of two of the dogs reported excellent outcomes without any long-term complications or tumour recurrence. The goal of this study was to describe the surgical technique for performing a crescentic osteotomy for resection of maxillary and mandibular tumours.
Category: Oncology
Journal: VCOT
This case report describes the diagnosis and management of primary femoral nerve sheath tumours in two dogs. Both of the tumours were localised by electromyography (EMG) and magnetic resonance imaging (MRI), and were then surgically resected using a novel approach to the iliopsoas muscle via osteotomy of the ventral ilial wing. This approach should be considered when attempting surgical treatment of conditions affecting the iliopsoas muscle or the femoral nerve because it provides excellent exposure of these structures.
Category: Oncology
Journal: Can Vet J
Multilobular osteochondrosarcoma (MLO) of the os penis was diagnosed in a dysuric dog. Recurrence was confirmed or suspected twice over a 22-month period. This is the first reported case of MLO occurring in the os penis, and the 5th reported case of neoplasia of the os penis in the dog.
Category: Oncology
Journal: J Feline Med Surg
Multilobular tumour of bone is a rare neoplasm of the skull in middle-aged, medium-to-large breed dogs even if a few cases have also been described in cats and one horse. The aim of the present paper is to show both the computed-tomography features and the pathological findings of the above neoplasm affecting the thoracic wall of a cat. To the best of the authors' knowledge, such anomalous tumour localisation has never been reported and imaged in feline medicine.
Category: Oncology
Journal: J Feline Med Surg
An 11-year-old neutered male domestic shorthair cat was presented with an epulis. A hemispherical mass, 8mm in maximum diameter, without a peduncle and bright reddish in colour, was observed on the gingiva of the left mandible. Radiography failed to show any infiltrating osteolysis. The epulis was surgically removed via gingival incision around the margin to the depth of connective tissue layer. Histopathological examination indicated that the epulis contained a large number of multinucleated giant cells (MGCs) intermixed with mononuclear mesenchymal cells in a loose fibrovascular stroma.
Category: Oncology
Journal: Aust Vet J
Osteosarcoma of the penile bone was diagnosed in a 5-year-old neutered male Rottweiler with recurrent dysuria. Imaging and cytological findings raised the suspicion for an osteosarcoma and ablation of the entire penis and scrotal urethrostomy was performed. The diagnosis was confirmed histologically. The dog recovered well and no postoperative signs of dysuria were observed. The dog survived without adjuvant chemotherapy for 12 months when multiple tumours in the thorax and abdomen led to it being euthanased.
Category: Oncology
Journal: AJVR
Objective-To develop an IM xenograft model of canine osteosarcoma in mice for the purpose of evaluating effects of radiation therapy on tumors. Animals-27 athymic nude mice. Procedures-Mice were randomly assigned to 1 of 3 groups of 9 mice each: no treatment (control group), radiation at 10 Gy, or radiation at 15 Gy. Each mouse received 5 x 10(5) highly metastasizing parent osteosarcoma cells injected into the left gastrocnemius muscle. Maximum tumor diameter was determined with a metric circles template to generate a tumor growth curve.
Category: Oncology