Oncology

Authors: Farese JP, Kirpensteijn J, Kik M, Bacon NJ, Waltman SS, Seguin B, Kent M, Liptak J, Straw R, Chang MN, Jiang Y, Withrow SJ.
Journal: Vet Surg

OBJECTIVE: To characterize biologic behavior, clinical outcome, and effect of histologic grade on prognosis for dogs with appendicular chondrosarcoma treated by amputation alone. STUDY DESIGN: Case series. ANIMALS: Dogs (n=25) with appendicular chondrosarcoma. METHODS: Medical records were searched to identify dogs with appendicular chondrosarcoma treated by limb amputation alone. Information recorded included signalment, anatomic location, radiographic appearance, and development of metastasis. Histopathologic diagnosis was confirmed and graded (1, 2, or 3).

Category: Oncology
Authors: Weinstein JI, Payne S, Poulson JM, Azuma C.
Journal: Vet Rad US

A standard of therapy for osteosarcoma includes amputation with or without adjuvant chemotherapy. There is a subset of dogs with osteosarcoma that are unsuitable for amputation. We evaluated kinetic variables in dogs with appendicular osteosarcoma treated with a single 8 Gy dose of radiation. Eighteen pet dogs with appendicular osteosarcoma received one 8 Gy fraction of palliative radiation on day 0. Force plate measurements and clinical assessments were made on days 0, 7, 14, and 21. Peak vertical forces (Fz) were recorded for each limb and a symmetric index (SI) was calculated.

Category: Oncology
Authors: Böttcher P, Krastel D, Hierholzer J, Westphalen K, Florian S, Hildebrandt G, Vera G, Oechtering G.
Journal: Vet Surg

OBJECTIVE: To (1) evaluate the analgesic effect of percutaneous cementoplasty (PC) in dogs with primary bone tumor (PBT) of the distal aspect of the radius and (2) evaluate the impact on the course of disease by adding PC to a palliative, multimodal treatment protocol in these dogs. STUDY DESIGN: Prospective pilot study. ANIMALS: Dogs (n=4) with PBT of the distal aspect of the radius. METHODS: Tumor lesions were filled percutaneously with polymethylmethacrylate under fluoroscopic guidance. Pamidronate was administered once in a week before PC.

Authors: Reynolds D, Fransson B, Preston C.
Journal: VCOT

Rim resection of mandibular tumours and a simplified technique using a biradial osteotomy blade for maxillary tumours in dogs has not previously been described. The medical records and radiographs of dogs with mandibular (n = 3) or maxillary (n = 1) tumours resected using crescentic osteotomies were reviewed. The owners of two of the dogs reported excellent outcomes without any long-term complications or tumour recurrence. The goal of this study was to describe the surgical technique for performing a crescentic osteotomy for resection of maxillary and mandibular tumours.

Category: Oncology
Authors: Harcourt-Brown T, Granger N, Smith P, Hughes K, Jefferey N.
Journal: VCOT

This case report describes the diagnosis and management of primary femoral nerve sheath tumours in two dogs. Both of the tumours were localised by electromyography (EMG) and magnetic resonance imaging (MRI), and were then surgically resected using a novel approach to the iliopsoas muscle via osteotomy of the ventral ilial wing. This approach should be considered when attempting surgical treatment of conditions affecting the iliopsoas muscle or the femoral nerve because it provides excellent exposure of these structures.

Category: Oncology
Authors: Webb JA, Liptak JM, Hewitt SA, Vince AR.
Journal: Can Vet J

Multilobular osteochondrosarcoma (MLO) of the os penis was diagnosed in a dysuric dog. Recurrence was confirmed or suspected twice over a 22-month period. This is the first reported case of MLO occurring in the os penis, and the 5th reported case of neoplasia of the os penis in the dog.

Category: Oncology
Authors: Chang SC, Liao JW, Liu CI, Wong ML, Cheng FP.
Journal: J Feline Med Surg

An 11-year-old neutered male domestic shorthair cat was presented with an epulis. A hemispherical mass, 8mm in maximum diameter, without a peduncle and bright reddish in colour, was observed on the gingiva of the left mandible. Radiography failed to show any infiltrating osteolysis. The epulis was surgically removed via gingival incision around the margin to the depth of connective tissue layer. Histopathological examination indicated that the epulis contained a large number of multinucleated giant cells (MGCs) intermixed with mononuclear mesenchymal cells in a loose fibrovascular stroma.

Category: Oncology
Authors: Rossetti E, Bertolini G, Zotti A.
Journal: J Feline Med Surg

Multilobular tumour of bone is a rare neoplasm of the skull in middle-aged, medium-to-large breed dogs even if a few cases have also been described in cats and one horse. The aim of the present paper is to show both the computed-tomography features and the pathological findings of the above neoplasm affecting the thoracic wall of a cat. To the best of the authors' knowledge, such anomalous tumour localisation has never been reported and imaged in feline medicine.

Category: Oncology
Authors: Peppler C, Weissert D, Kappe E, Klump S, Kramer M, Reinacher M, Neiger R.
Journal: Aust Vet J

Osteosarcoma of the penile bone was diagnosed in a 5-year-old neutered male Rottweiler with recurrent dysuria. Imaging and cytological findings raised the suspicion for an osteosarcoma and ablation of the entire penis and scrotal urethrostomy was performed. The diagnosis was confirmed histologically. The dog recovered well and no postoperative signs of dysuria were observed. The dog survived without adjuvant chemotherapy for 12 months when multiple tumours in the thorax and abdomen led to it being euthanased.

Category: Oncology
Authors: Phillips B, Powers BE, Dernell WS, Straw RC, Khanna C, Hogge GS, Vail DM.
Journal: JAAHA

Survival following amputation and administration of single-agent carboplatin for treatment of appendicular osteosarcoma (OSA) in dogs was retrospectively examined. Records of 155 dogs with appendicular OSA treated with amputation and single-agent carboplatin were included from 14 centers. Any carboplatin dosage, number of doses, and protocol schedule were eligible for inclusion. The median disease-free interval (DFI) was 256 days. The median overall survival time was 307 days.

Category: Oncology