Osteoarthritis

Authors: Greene LM, Marcellin-Little DJ, Lascelles BD.
Journal: JAVMA

Objective-To evaluate factors associated with lameness severity and hip joint range of motion in dogs with hip dysplasia and to assess the association between hip joint range of motion and degree of lameness. Design-Prospective case series. Animals-60 client-owned Labrador Retrievers with hip dysplasia. Procedures-Owners completed a questionnaire regarding their dogs' daily exercise duration and type (ie, low impact vs high impact) and lifestyle. Range of motion of affected hip joints was measured with a transparent plastic goniometer.

Authors: Brady RB, Sidiropoulos AN, Bennett HJ, Rider PM, Marcellin-Little DJ, Devita P.
Journal: AJVR

Objective-To assess differences in sagittal plane joint kinematics and ground reaction forces between lean and obese adult dogs of similar sizes at 2 trotting velocities. Animals-16 adult dogs. Procedures-Dogs with body condition score (BCS) of 8 or 9 (obese dogs; n = 8) and dogs with BCS of 4 or 5 (lean dogs; 8) on a 9-point scale were evaluated. Sagittal plane joint kinematic and ground reaction force data were obtained from dogs trotting at 1.8 and 2.5 m/s with a 3-D motion capture system, a force platform, and 12 infrared markers placed on bony landmarks.

Authors: Gao X, Lee J, Malladi S, Melendez L, Lascelles BD, Al-Murrani S.
Journal: J Feline Med Surg

The underlying disease mechanisms for feline degenerative joint disease (DJD) are mostly unidentified. Today, most of what is published on mammalian arthritis is based on human clinical findings or on mammalian models of human arthritis. However, DJD is a common occurrence in the millions of domestic felines worldwide.

Authors: Klinck MP, Frank D, Guillot M, Troncy E.
Journal: Can Vet J

Veterinarians contacted to identify cats diagnosed with osteoarthritis (OA) provided information on signalment, method of diagnosis, treatment and concurrent disease. Owners of 50 cats were interviewed to collect information on specific OA signs observed in the home, relating to mobility, self-maintenance, social and exploratory behavior, and activity and habits at diagnosis and after treatment. Mean age at diagnosis was 12 y; concurrent diseases were common (44%).

Authors: Sullivan MO, Gordon-Evans WJ, Knap KE, Evans RB.
Journal: Vet Surg

OBJECTIVES:
To evaluate the efficacy of pulsed signal therapy (PST) in reducing pain and increasing function in dogs with osteoarthritis (OA) using a randomized, blinded, controlled clinical trial.
STUDY DESIGN:
Randomized, controlled, blinded clinical trial.
ANIMALS:
Adult dogs (n = 60) with moderate-to-severe clinical signs of OA.
METHODS:

Authors: Dingemanse WB, Van Bree HJ, Duchateau L, Gielen IM.
Journal: Vet Surg

OBJECTIVE:
To evaluate clinical and subchondral bone lesion differences between medial (MTRT-OC) and lateral trochlear ridge tarsocruralosteochondrosis (LTRT-OC).
STUDY DESIGN:
Retrospective case series.
ANIMALS:
Dogs (n = 66) with MTRT-OC or LTRT-OC.
METHODS:

Authors: Safra N, Johnson EG, Lit L, Foreman O, Wolf ZT, Aguilar M, Karmi N, Finno CJ, Bannasch DL.
Journal: JAVMA

Objective-To evaluate clinical manifestations, response to treatment, and outcome for Weimaraners with hypertrophic osteodystrophy (HOD). Design-Retrospective case series. Animals-53 dogs. Procedures-Medical records were reviewed for signalment, vaccination history, clinical signs, laboratory test results, response to treatment, and relapses. Radiographs were reviewed. Results-Clinical signs included pyrexia, lethargy, and ostealgia; signs involving the gastrointestinal, ocular, or cutaneous systems were detected. Of the 53 dogs, 28 (52.8%) had HOD-affected littermates.

Authors: Deluke AM, Allen DA, Wilson ER, Lineberger JA, Lehenbauer TW, Fabiani M, Poteet BA.
Journal: Can Vet J

Radiographic osteoarthritis scores were determined in 60 dogs up to 3 years following tibial plateau leveling osteotomy. Radiographs taken immediately following surgery and at long-term follow-up 1 to 3 years later were evaluated by 2 certified radiologists using a modified 32-point osteoarthritis scale. Changes in osteoarthritis scores were evaluated by paired t-tests and regression analysis. Sub-groups of dogs were formed to evaluate if osteoarthritis scores changed differently for follow-up periods of < 24 months compared with those > 24 months.

Authors: Ondreka N, Amort KH, Stock KF, Tellhelm B, Klumpp SW, Kramer M, Schmidt MJ.
Journal: Vet J

The aim of this study was to identify skeletal variations in the lumbosacral junction (LSJ) of the German shepherd dog (GSD) compared with other large breeds. The radiographic traits of the LSJ were investigated in a group of 733 GSDs and a control group of 334 dogs of other breeds that were matched in terms of size. Nine morphological and 17 morphometric traits were recorded and analysed. Furthermore, the possibility of a genetic basis for these radiographic features was evaluated by calculation of genetic variance components.

Authors: Christopher SA, Beetem J, Cook JL.
Journal: Vet Surg

329-34OBJECTIVE: To evaluate long-term (>1 year) outcomes with respect to function and complications in dogs undergoing TightRope (TR), tibial plateau leveling osteotomy (TPLO), or tibial tuberosity advancement (TTA) for treatment of cranial cruciate liga