Osteoarthritis

Homing of xenogeneic MSCs to a naturally occurring joint lesion after IV administration.
Local sustained release of CXB is less suitable to treat acute inflammation in arthritic joints.
This reproducible scheme is easy to execute and sensitive to minimal OA progression without using computer software.
OA changes significantly progressed in the MIA + Tramadol group compared to the MIA + Vehicle group.
The rate of progression of radiographically assessed coxofemoral OA varies greatly.
There is good evidence of a high prevalence of OA and DJD in older cats.
Lameness may be scored after gait evaluation in dogs with elbow OA irrespective of the timing of a comprehensive orthopedic examination.
This review suggests that in animal models, structural onset of knee OA occurs either in bone prior to cartilage pathology or simultaneously.