Further long-term investigations on specific BCP efficacy in horses with osteoarthritis, preferably in blinded and placebo-controlled studies, should be performed to confirm these first positive results.
These results provide further indication that vitacoxib is safe and well-tolerated in rats after 180 days of daily oral administration at 6 mg/kg bw and the NOAEL for both sexes was 6 mg/kg bw for 180 consecutive days.
Future research focused on key active ingredients would enable consistent and improved efficacy from GSM-based products for the purpose of improved animal health.
Low overall variabilities among the 15 independent measures of the OA scoring system presented
Meloxicam OTMS had similar effects on peak vertical force, motor activity and pain sensitization as previously reported for oral meloxicam in OA cats
Synovitis and changes in the subchondral bone and calcified cartilage may be important in the pathogenesis of this condition
There is good diagnostic agreement between synovial fluid effusion and osteophytosis when dealing with stifle joint OA