Gastrocnemius tendon strain in a dog treated with autologous mesenchymal stem cells and a custom orthosis.

Authors: 
Case JB, Palmer R, Valdes-Martinez A, Egger EL, Haussler KK.
Volume: 
42
Number: 
4
Pages: 
355-60
Journal: 
Vet Surg
Date: 
2013 May

OBJECTIVE:
To report clinical findings and outcome in a dog with gastrocnemius tendon strain treated with autologous mesenchymal stem cells and a custom orthosis.
STUDY DESIGN:
Clinical report.
ANIMAL:
A 4-year-old spayed female Border Collie.
METHODS:
Bone-marrow derived, autologous mesenchymal stem cells were transplanted into the tendon core lesion. A custom, progressive, dynamic orthosis was fit to the tarsus. Serial orthopedic examinations and ultrasonography as well as long-term force-plate gait analysis were utilized for follow up.
RESULTS:
Lameness subjectively resolved and peak vertical force increased from 43% to 92% of the contralateral pelvic limb. Serial ultrasonographic examinations revealed improved but incomplete restoration of normal linear fiber pattern of the gastrocnemius tendon.
CONCLUSIONS:
Findings suggest that autologous mesenchymal stem cell transplantation with custom, progressive, dynamic orthosis may be a viable, minimally invasive technique for treatment of calcaneal tendon injuries in dogs.