Cell-based Therapies for Equine Joint Disease

Authors
David D. Frisbie, Matthew C. Stewart
Date
August 2011
Journal
Veterinary Clinics of North America: Equine Practice
Volume
27
Number
2
Pages
335-349

Joint disease is a major cause of wastage in performance horses. Arthritis can be challenging to treat because articular cartilage has little or no capacity for repair, therapeutic options are limited and are largely targeted at ameliorating clinical signs of joint disease. Cell-based therapies have potential to overcome the intrinsic constraints to articular cartilage repair. This article focuses on cell-based therapies for treatment of equine joint disease. Results from experimental model and human clinical studies are presented along with available data from equine studies.