Adult Multipotent Stromal Cell Technology for Bone Regeneration: A Review

Authors
Mandi J. Lopez DVM, MS, PhD, Diplomate ACVS, Patrick R. Daigle
Date
January 2013
Journal
Veterinary Surgery
Volume
42
Number
1
Pages
1-11

Since the discovery of bone marrow derived stromal cell osteogenesis in the 1960s, tissue engineering with adult multipotent stromal cells (MSCs) has evolved as a promising approach to restore structure and function of bone compromised by injury or disease. To date, accelerated bone formation with MSCs has been demonstrated with a variety of tissue engineering strategies. Though MSC bone tissue engineering has advanced over the last few decades, limitations to clinical translation remain. A current review of this promising field is presented with a specific focus on equine investigations.

Equine
Stem cells

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